Increased cell survival through protection against free-radical damage
10.1021/acs.jafc.4c08428 99 LiuJ.LiuZ.LiX.ZhuL.XuG.ChenZ.et al (2020)
Furthermore, certain spontaneous reports lacked validation from healthcare professionals, and there was an absence of data regarding the patients physical conditions, familial history, and individual histories of alcohol and tobacco use, all of which could potentially affect cancer development
This is due to overstimulation by GLP-1 agonists, which can then lead to hyperplasia and subsequent pancreatitis
In human case reports, exposure to SGLT2 inhibitors was associated with a higher than expected incidence of congenital malformations, such as hydrocephalus, encephalocele, renal aplasia and esophageal atresia, as well as miscarriages